Should I move to St. Louis, MO or Charlotte, NC?

I know that Charlotte has better weather, (which is why it sparked my interest) but the drawback is that I don't know if I can adjust (or want to adjust) to the southern lifestyle, since I'm from the midwest. St. Louis on the otherhand isn't half as pretty and but I would feel more comfortable around the people since it's located in the midwest. Which one should I choose?